Empresa: MSD
Job Description Our Global Clinical Trial team is at the heart of advancing our clinical development portfolio, turning science into meaningful outcomes for patients. We are looking for a Clinical Research Manager (CRM) to drive the end-to-end execution of clinical studies in Brazil. This role is primarily accountable for the end to end performance and project management for assigned protocols in a country in compliance with ICH/GCP and country regulations, our company policies and procedures, quality standards and adverse event reporting requirements internally and externally. Responsibilities include, but are not limited to : Main Point of Contact (POC) for assigned protocols and link between Country Operations and clinical trial team (CTT). • Responsible for project management of the assigned studies: pro-actively plans, drives and tracks execution and performance of deliverables/timelines/results to meet country commitments from feasibility and site selection, recruitment, execution and close out. • Accountable for performance for assigned protocols in a country in compliance with ICH/GCP and country regulations, Our Company policies and procedures, quality standards and adverse event reporting requirements internally and externally. • Reviews Monitoring Visits Reports and escalates performance issues and training needs to CRA manager and/or functional vendor and internal management as needed. • Performs Quality control visits as required • Leads local study teams to high performance: trains in the protocol other local roles, closely collaborates with and supports CRAs as protocol expert and coordinates activities across the different local country roles ensuring a strong collaboration • Responsible for creating and executing a local risk management plan for assigned studies • Ensures compliance with CTMS, eTMF and other key systems in assigned studies • Escalates as needed different challenges and issues to TA Head/CRD/CQM and or CTT (as appropriate) Responsible for collaboration with functional outsourcing vendors, investigators, other external partners in assigned studies: • Country POC for programmatically outsourced trials for assigned protocols. • Collaborates internally with HQ functions and locally with PV, Regulatory and GMA to align on key decisions in his/her studies. GHH to be consulted as needed. • As a customer-facing role, this position will build business relationships and represent Our Company with investigators • Shares protocol-specific information and best practices across countries\clusters Required Experience • Proven hands-on experience in end-to-end management of sponsor-led Phase I–III clinical trials, beyond site monitoring activities. • Experience managing large-scale and/or highly complex clinical trials, including megatrials. • Experience with complex study designs and operational models, with greater emphasis on study type, scale and complexity than on a specific therapeutic area. • Strong knowledge of ICH-GCP, clinical research regulations and quality standards. • Strong project management, risk management and cross-functional stakeholder management capabilities Required : • Bachelor degree in Science (or comparable) • English Proficiency Preferred : Advanced degree, (e.g., Master degree, MD, PhD) "Temos orgulho de ser uma empresa que acredita no valor de trazer pessoas de diferentes perfis, talentosas e comprometidas. A maneira mais rápida de revolucionar a inovação é quando ideias diversas se reúnem em um ambiente inclusivo. Incentivamos nossos colaboradores a abordar os problemas coletivamente e desafiar de forma respeitosa o raciocínio uns dos outros. Somos um empregador focado em promover iguais oportunidades aos nossos colaboradores, comprometido a incentivar um local de trabalho inclusivo e diversificado." Additional location(s) Compensation Information: Required Skills: Clinical Data Management, Clinical Research, Clinical Site Management, Clinical Trial Management, Good Clinical Practice (GCP), Risk Based Monitoring, Strategic Planning, Strategic Thinking, Vendor Management Preferred Skills: Current Employees apply HERE Current Contingent Workers apply HERE Search Firm Representatives Please Read Carefully Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails. Employee Status: Regular Relocation: VISA Sponsorship: Travel Requirements: Flexible Work Arrangements: Hybrid Shift: Valid Driving License: Hazardous Material(s): Job Posting End Date: 11/18/2026 *A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.